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The patient-Derived Xenografts (PDX) are preclinical cancer models developed by implanting tumor tissues directly from a patient into immunocompromised or humanized mice. These models preserve the original tumor's histological architecture, genetic makeup, and heterogeneity, making them valuable too...

Interferon-gamma (IFN-γ) is a critical cytokine in the immune system, playing a central role in immune responses against infections, cancer, and autoimmune conditions. The measurement of IFN-γ levels is pivotal in immunological research, vaccine development, and disease monitoring. Among the widely ...

Historically, microbial identification relied on phenotypic methods such as culture-based techniques and biochemical assays. While these methods remain foundational, they are often time-consuming and limited to culturable organisms. In contrast, modern molecular approaches leverage nucleic acid-base...

Exosomes have emerged as a promising tool for drug delivery due to their ability to efficiently transport therapeutic molecules across biological barriers. One of the most exciting areas of research is their potential in targeting the brain, especially in the treatment of neurological disorders. Exo...

As a senior expert in antibody development, Creative Biolabs owns lots of scientists who are proficient in non-IgG therapeutic antibody production, engineering, and application. Our professional scientists are pleased to provide the custom non-IgG antibody isotype switching service against diverse d...

Cell proliferation is a fundamental process in which cells undergo division and increase in number, playing a crucial role in growth, development, and tissue repair. During cell proliferation , various signaling pathways are activated to regulate the cell cycle, ensuring proper progression through i...

The ADC manufacturing process plays a critical role in the development of antibody-drug conjugates (ADCs), which are designed to deliver potent cytotoxic drugs directly to cancer cells, minimizing damage to healthy tissues. This process involves several key stages, including the conjugation of cytot...

Plasminogen Activator Inhibitor (PAI) refers to proteins that regulate fibrinolysis by inhibiting plasminogen activators. The most studied PAI is plasminogen activator inhibitor -1 (PAI-1), a key regulator of blood clot dissolution and other physiological processes such as tissue remodeling and woun...

The custom assay development is a specialized service tailored to design, optimize, and validate assays for specific research, diagnostic, or therapeutic applications. This approach ensures that the assay meets the unique requirements of a project, addressing challenges such as sensitivity, specific...

The NCI-H3122 cell line is a non-small cell lung cancer (NSCLC) cell line derived from a human lung adenocarcinoma. It is widely used in cancer research, particularly in studies involving lung cancer, molecular oncology, and drug development. Below are key details about the NCI-H3122 cell line: Gene...